Endocrine Abstracts

Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder accompanied by high cytokines and low total 25-hydroxyvitamin D [25(OH)D]. An inflammatory cytokine, monocyte chemoattractant protein-1 (MCP-1), is found to be higher in people with elevated parathyroid hormone (PTH), unlike other cytokines (1). Also, a rise in MCP-1 in response to high PTH is associated with bone loss (2). Parathyroidectomy (PTX) is the only cure for patients with PHPT. Whether the ...